Serum Levels of 8-hydroxy-deoxyguanosine under the Chemicals Influence
نویسندگان
چکیده
LUCIA DINU1, CORINA DANIELA ENE (NICOLAE)2, ILINCA NICOLAE3*, MIRCEA TAMPA2,3, CLARA MATEI2, SIMONA ROXANA GEORGESCU2,3 1 MedLife Clinic, 1 Hans Christian Andersen Str., 040289, Bucharest, Romania 2 University of Medicine and Pharmacy Carol Davila, 8 Eroii Sanitari Blvd., 060474, Bucharest, Romania 3 Victor Babes Hospital of Clinical and Infectious Diseases, 281 Mihai Bravu Blvd, 030303, Bucharest, Romania
منابع مشابه
Serum 8-hydroxy-2-deoxyguanosine as a marker of DNA oxidative damage in horses with recurrent airway obstruction
BACKGROUND It has been reported that equine recurrent airway obstruction (RAO) is a state of oxidative stress. Oxidant-antioxidant imbalance is known to increase the conversion of deoxyguanosine to 8-hydroxy-2-deoxyguanosine (8-OHdG) in DNA. 8-OHdG can easily be measured using ELISA tests in serum or urine samples. In this study, we analysed serum 8-OHdG levels in horses with recurrent airway o...
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INTRODUCTION AND OBJECTIVES Heart failure is associated with increased free radical production, which leads to a state of oxidative stress. Known markers of oxidative stress include 8-hydroxy-2'-deoxyguanosine, which reflects oxidative damage to DNA, and lipid peroxidation, which can be used to quantify damage to lipid-rich structures. The aims of this study were to compare 8-hydroxy-2'-deoxygu...
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Received: 16 Aug , 2015 Accepted: 22 Oct , 2015 Abstract Background & Aims: The aim of this study was to evaluate serum levels of antioxidant property Klotho by examining 8-hydroxy-2'- deoxyguanosine (8-OHdG), as a marker of oxidative damage in nucleic acids in patients with hemodialysis and kidney transplantation. Materials & Methods: Serum samples from 45 patients undergoing hem...
متن کاملاثر هشت هفته تمرینات هوازی بر برخی شاخص‌های استرس اکسیداتیو زنان سالمند
Objectives Oxidative stress has an important role in the pathogenesis of diseases such as cardiovascular disease, cancer, diabetes and aging. The present study investigated the effects of 8 weeks of aerobic training on 8-hydroxy-2′-deoxyguanosine and body composition in elderly women. Methods & Materials This was a quasi-experimental study. The study participants were selected by convenience s...
متن کاملMetal nanoparticle-induced micronuclei and oxidative DNA damage in mice
Several mechanisms regarding the adverse health effects of nanomaterials have been proposed. Among them, oxidative stress is considered to be one of the most important. Many in vitro studies have shown that nanoparticles generate reactive oxygen species, deplete endogenous antioxidants, alter mitochondrial function and produce oxidative damage in DNA. 8-Hydroxy-2'-deoxyguanosine is a major type...
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تاریخ انتشار 2014